Putting $$$ aside. I cannot attest to the 6th Gen, but we do have both GX and 4R. The GX is what we call our vacation car. The GX sits in the garage until its road trip time. My wife drives the 4r as a daily driver, she used to have a highlander for a daily driver, but we trashed that for the GX and swapped her out to the 4R. We enjoy the extra space of the GX for the road trips but still struggle with enough room up front for all our coffee cups, laptop, phones, etc. Rationalize for owning both...., who cares if you can afford it. After all its only money and you can't take it with you.